Drug Discovery

Drug Discovery

As researchers to identify the right target and select molecules with suitable characteristics modulate it, M&S supports both proof of mechanism analyses (proximal PK & PD effects) while also providing an early sense for ‘proof of concept’ downstream effects in the clinic.

At Vantage, our focus in drug discovery has been on

  • Connect Target-Pathway-Disease
  • Identify optimal molecule characteristics and support lead selection

Key Questions that M&S can address

  • Based on target binding data, can we decide which molecule has the optimal characteristics to become a lead candidate?
  • Can we predict downstream effects of modulating this target and estimate the effect on ultimate PD biomarkers measured in the clinic?

Case Studies

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